Re 5:1
5:1 And {1} I saw in the {2} right hand of him that sat on the
    throne {3} a book written within and on the backside, sealed
    with seven seals.

 (1) A passing to the second principal cause, which is the Son
     of God, God and man, the mediator of all, as the eternal
     word of God the Father, manifest in the flesh.  This
     chapter has two parts: one that prepares the way to the
     revelation, by rehearsal of the occasions that occurred in
     the first four verses Re 5:2-5. Another, the history
     of the revelation of Christ, from there to the end of the
     chapter Re 5:6-14.
 (2) That is, in the very right hand of God.
 (3) Here are shown the occasions for which the principal cause,
     and this revelation was also necessary: the same are three,
     the first a present vision of the book of the counsels of
     God, concerning the government of this whole world, which
     book is said to be laid up with the Father as it were in
     his hand: but shut up and unknown to all creature, in this
     verse.  The second is a religious desire of the angels of
     God to understand the mysteries of this book 1Pe 1:12,
     Re 5:2. The third is a lamentation of John and all the
     godly, moved by the same desire Re 5:4 when they
     saw that it was an impossible thing for any creature to
     do: which is declared in Re 5:3.

Re 5:3
5:3 {4} And no man in heaven, nor in earth, neither under the
    earth, was able to open the book, neither to look thereon.

 (4) Thus neither of them that are in heaven, nor of them who
     are in the earth.  Now this counting of parts, is
     sufficient to the denying of the whole; For of the
     creatures, one sort is in heaven, above the earth: another
     in the earth, and another under the earth in the sea, as is
     later declared in Re 5:13.

Re 5:5
5:5 {5} And one of the elders saith unto me, Weep not: behold,
    the {6} Lion of the tribe of Juda, the Root of David, hath
    prevailed to open the book, and to loose the seven seals
    thereof.

 (5) The second part of this chapter, in which is set down the
     revelation of the Son, as was said before.  This part
     contains first a history of the way God prepared John to
     understand this revelation, in this verse.  Secondly, the
     revelation of the Son himself, to Re 5:6,7.  Thirdly,
     the events of this revelation in the rest of the chapter.
     The manner now, is here described in two parts: one from
     outside him, by speech, in this verse: another within, by
     opening the eyes of John (which before were shut) that he
     might see, in the verse following.
 (6) That is, most mighty and most approved Prince: according to
     the use of the Hebrew speech.

Re 5:6
5:6 And I beheld, and, lo, {7} in the midst of the throne and of
    the four beasts, and in the midst of the elders, stood a
    Lamb as it had been slain, having seven horns and seven
    eyes, which are the seven Spirits of God sent forth into all
    the earth.

 (7) The sum of this revelation: Christ the mediator takes and
     opens the book Re 5:6,7.  Therefore this revelation
     describes the person of Christ. The person is described
     this way: Christ the mediator between God, angels and men,
     as the eternal word of God, and our redeemer: as the Lamb
     of God, standing as slain and making intercession for us by
     the power and merit of his everlasting sacrifice, is armed
     with the Spirit of God, that is, with the power and wisdom
     of God effectually to the government of this whole world.

Re 5:7
5:7 {8} And he came and took the book out of the right hand of
    him that sat upon the throne.

 (8) The fact of Christ the Mediator: that he comes to open it.
     That he opened it is first expressed Re 6:1.

Re 5:8
5:8 {9} And when he had taken the book, the four beasts and four
    [and] twenty elders fell down before the Lamb, having every
    one of them {10} harps, and golden vials full of odours,
    which are the {a} prayers of saints.

 (9) Now follows the end, the events of the revelation previously
     spoken of: that all the holy angels and men sang to him:
     both the chief Re 5:9,10 and common order of angels
     Re 5:11,12 and of all things created Re 5:11,12
     the princes of both sorts agreeing to it, Re 5:14.
 (10) The symbols or signs of praise, sweet in savour and
      acceptable to God;
    (a) See Re 8:3.

Re 5:9
5:9 And they sung a {b} new {11} song, saying, {12} Thou art
    worthy to take the book, and to open the seals thereof: for
    thou wast slain, and hast redeemed us to God by thy blood
    out of every kindred, and tongue, and people, and nation;

    (b) No common song.
 (11) That is, composed according to the present matter, the
      Lamb having received the book as it were with his feet and
      opened it with his horns, as it is said in the Song of
      Solomon
 (12) The song of the nobles or princes standing by the throne,
      consisting of a publication of the praise of Christ and a
      confirmation of the same from his blessings, both which we
      have received from him (as are the suffering of his death,
      our redemption upon the cross by his blood, in this verse:
      and our communion with him in kingdom and priesthood which
      long ago he has granted to us with himself and which we
      hereafter hope to obtain, as our kingdom to come, in
      Christ, Re 5:10.

Re 5:11
5:11 {13} And I beheld, and I heard the voice of many angels
     round about the throne and the beasts and the elders: {14}
     and the number of them was {c} ten thousand times ten
     thousand, and thousands of thousands;

 (13) The consent of the common order of angels, answering in
      melody to their princes that stood by the throne.
 (14) A finite number, but almost infinite, as in Da 7:10.
     (c) This means a great number.

Re 5:12
5:12 Saying with a loud voice, Worthy is the Lamb that was slain
     to {d} receive power, and riches, and wisdom, and strength,
     and honour, and glory, and blessing.

     (d) To have all praise given to him, as to the mightest and
         wisest

Re 5:13
5:13 {15} And every creature which is in heaven, and on the
     earth, and under the earth, and such as are in the sea, and
     all that are in them, heard I saying, Blessing, and honour,
     and glory, and power, [be] unto him that sitteth upon the
     throne, and unto the Lamb for ever and ever.

 (15) The consent of all the common multitude of the creatures.

Re 5:14
5:14 {16} And the four beasts said, Amen. And the four [and]
     twenty elders fell down and worshipped him that liveth for
     ever and ever.

 (16) A confirmation of the praise given before, from the
      consent of the nobles, expressed in word and signs, as
      once or twice before this.